
Southern Louisiana Vacations from $285
Book a Hotel + Flight or Car together to unlock savings
- Plan, book, travel with confidence
Better together
Find the right fit
Rest easy
Your Southern Louisiana Vacation
Choose a vacation package to Southern Louisiana and make planning your adventure quick and easy. With the finer details arranged before you leave, you can focus on enjoying every moment in this amazing destination. Your trip to Southern Louisiana wouldn't be complete without exploring some of its most renowned cities, starting with Lake Charles. Two of the top attractions here include Golden Nugget and Horseshoe Lake Charles Casino. Lafayette is another favorite with Southern Louisiana travelers. Visitors to this city enjoy Acadian Village and CIty Club at River Ranch. Expedia has everything you need for planning your Southern Louisiana vacation. From flights and hotels, to rental cars and more, we're here to help you curate a travel experience like no other.
The Latest Southern Louisiana vacation packages


Hotel Perle
Reviewed on Jul 22, 2025

Maison Dupuy Hotel
Reviewed on Aug 4, 2025

The Barnett, part of JdV by Hyatt
Reviewed on Aug 4, 2025

Wyndham New Orleans - French Quarter
Reviewed on Aug 4, 2025
Where to stay in Southern Louisiana

River Ranch
While River Ranch might not have many sights to explore, venturing just a little farther will lead you to top things to see and do like Acadiana Mall and Blackham Coliseum.
Discover the most popular places to visit in Southern Louisiana

Golden Nugget
Why not try your luck with a visit to Golden Nugget where you can enjoy the entertainment at this popular casino in Lake Charles? Check out the casinos and top-notch restaurants in this family-friendly area.

North Beach Interstate 10
Dip your toes into the water of Lake Charles, spot alligators, enjoy pretty sunsets and watch yacht races at this urban beach.

Acadian Village
The fascinating life of the Acadians of Louisiana comes alive at a collection of historic buildings, including a blacksmith workshop and church.
Southern Louisiana Hotel Deals

L'Auberge Casino Resort Lake Charles
Reviewed on Aug 5, 2025

Golden Nugget Lake Charles
Reviewed on Aug 4, 2025

Delta Downs Racetrack Casino Hotel
Reviewed on Aug 3, 2025
More vacations you might like
Explore a world of travel with Expedia
Explore a world of travel with Expedia
- Duson Hotels
- Pet-friendly Hotels in Duson
- Motel 6 Hotels in Duson
- Motels in Duson
- Cheap Hotels in Duson
- Resorts & Hotels with Spas in Duson
- B&B in Duson
- Hotels with Hot Tubs in Duson
- 4 Star Hotels in Duson
- Cabin Rentals in Duson
- Cottages in Duson
- 3 Star Hotels in Duson
- Hotels with Connecting Rooms in Duson
- Guest Houses in Duson
- Casino Hotels in Duson
- Rayne Hotels
- Cabin Rentals in Rayne
- B&B in Rayne
- Cottages in Rayne
- Vacation Homes in Rayne
- 4 Star Hotels in Rayne
- Pet-friendly Hotels in Rayne
- Motels in Rayne
- Hotels with a Pool in Rayne
- Condo Rentals in Rayne
- 3 Star Hotels in Rayne
- Guest Houses in Rayne
- Hotels near Candyland Cottage & Ice Cream Shoppe
- West Lafayette Hotels
- Casino Hotels in West Lafayette
- Historic Hotels in West Lafayette
- Cheap Hotels in West Lafayette
- Apartments in West Lafayette
- Cottages in West Lafayette
- Cabin Rentals in West Lafayette
- 4 Star Hotels in West Lafayette
- La Quinta Inn & Suites Hotels in West Lafayette
- 5 Star Hotels in West Lafayette
- Pet-friendly Hotels in West Lafayette
- Extended Stay Hotels in West Lafayette
- Hotels with an Outdoor Pool in West Lafayette
- Hotels with Connecting Rooms in West Lafayette
- Scott Hotels
- Cheap Hotels in Scott
- Pet-friendly Hotels in Scott
- Cabin Rentals in Scott
- B&B in Scott
- Motels in Scott
- La Quinta Inn & Suites Hotels in Scott
- Golf Hotels in Scott
- 3 Star Hotels in Scott
- Extended Stay Hotels in Scott
- Luxury Hotels in Scott
- Hotels with Bars in Scott
- Vacation Homes in Scott
- 5 Star Hotels in Scott
- Cottages in Scott
- Hotels with a Pool in Scott
- Casino Hotels in Scott
- Hotels near Acadian Village
- Hotels near American Legion Hospital
- Crowley Hotels
- Hotels near St Michael The Archangel Church
- Rayne Vacations
- Visit Duson
- Visit Rayne
- Candyland Cottage & Ice Cream Shoppe
- West Lafayette Vacations
- Visit West Lafayette
- Begnaud House
- Scott Vacations
- Acadian Village
- American Legion Hospital
- Visit Scott
- St Michael The Archangel Church
- Crowley Vacations
- Martin Luther King Park
- Acadiana Mall
- Neyland Park
- Visit Crowley
- Car rentals near Duson
- Car rentals near Rayne
- Enterprise Rental Cars in Rayne
- Car rentals near West Lafayette
- Car rentals near Roberts Cove
- Enterprise Rental Cars in Scott
- Car rentals near Scott
- Car rentals near American Legion Hospital
- Car rentals near Crowley
- Car rentals near St Michael The Archangel Church